ANTHRANILATE SYNTHASE COMPONENT I Meaning and
Definition
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Anthranilate synthase component I, also known as TrpE, is an enzyme that plays a crucial role in the biosynthesis of the amino acid tryptophan. It is responsible for the first step in the pathway, which involves the conversion of chorismate to anthranilate.
Anthranilate synthase component I is a homodimeric enzyme, meaning it consists of two identical subunits. Each subunit contains two distinct domains - the N-terminal domain and the C-terminal domain. The N-terminal domain is responsible for binding and activating the chorismate substrate, while the C-terminal domain catalyzes the conversion to anthranilate.
The enzyme requires the presence of a cofactor called 5'-phosphoribosyl 1-pyrophosphate (PRPP) for its activity. PRPP acts as a donor of a pyrophosphate group, which is essential for the reaction to occur.
The catalytic mechanism of anthranilate synthase component I involves the rearrangement of the chorismate ring, leading to the formation of anthranilate. This reaction is facilitated by a number of conserved amino acid residues within the active site of the enzyme.
Overall, anthranilate synthase component I is a vital enzyme in tryptophan biosynthesis, as it initiates the conversion of chorismate to anthranilate. Its function is intricately linked to the synthesis of this essential amino acid, which is not only a building block for proteins but also serves as a precursor for various biologically active compounds.
Common Misspellings for ANTHRANILATE SYNTHASE COMPONENT I
- znthranilate synthase component i
- snthranilate synthase component i
- wnthranilate synthase component i
- qnthranilate synthase component i
- abthranilate synthase component i
- amthranilate synthase component i
- ajthranilate synthase component i
- ahthranilate synthase component i
- anrhranilate synthase component i
- anfhranilate synthase component i
- anghranilate synthase component i
- anyhranilate synthase component i
- an6hranilate synthase component i
- an5hranilate synthase component i
- antgranilate synthase component i
- antbranilate synthase component i
- antnranilate synthase component i
- antjranilate synthase component i
- anturanilate synthase component i
- antyranilate synthase component i
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