How Do You Spell ANTHRANILATE SYNTHASE?

1. Anthranilate synthase is an enzyme complex that plays a crucial role in the biosynthesis of the amino acid tryptophan. Tryptophan is an essential amino acid that is required for the proper growth and development of organisms. Anthranilate synthase is responsible for catalyzing the conversion of chorismate, a key precursor molecule, into anthranilate, which is an intermediate molecule in the tryptophan biosynthesis pathway.

   The enzyme complex consists of two subunits: α and β. The α-subunit of anthranilate synthase catalyzes the conversion of chorismate into anthranilate in a two-step reaction. First, chorismate is converted into a cyclic intermediate, isochorismate. Then, isochorismate is further transformed into anthranilate. The β-subunit, on the other hand, acts as a glutamine amidotransferase enzyme, providing the nitrogen source required for the amidation of anthranilate during the reaction.

   Anthranilate synthase is present in various organisms, including bacteria, fungi, and plants. It is a highly regulated enzyme complex, with its activity being modulated by several factors, such as the availability of substrates and feedback inhibition by tryptophan. The synthesis of anthranilate by anthranilate synthase is a key step in the overall tryptophan biosynthesis pathway, and its dysfunction can lead to an imbalance in tryptophan levels, affecting the overall metabolism and physiology of an organism.

Common Misspellings for ANTHRANILATE SYNTHASE

The word "Anthranilate Synthase" is derived from two components:

1. "Anthranilate": This term originates from the prefix "anthr-" which comes from the Greek word "anthos" meaning "flower". The word "anthranilate" refers to a specific molecule called anthranilic acid, which is involved in various metabolic pathways in living organisms.

2. "Synthase": This component comes from the suffix "-synthase", which is derived from the word "synthesis". Synthases are enzymes responsible for catalyzing or facilitating the synthesis or production of a specific molecule or compound in biological systems.

Therefore, "Anthranilate Synthase" refers to an enzyme responsible for the synthesis or production of anthranilate or related compounds.