TOSYLPHENYLALANYL CHLOROMETHYL KETONE Meaning and
Definition
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Tosylphenylalanyl Chloromethyl Ketone, also known by its abbreviation TPCK, is a chemical compound used primarily in biological research and proteomics. It is a member of the chloromethyl ketone family and consists of a tosylphenylalanyl moiety attached to a chloromethyl ketone functional group.
TPCK is frequently used as an irreversible inhibitor of serine proteases, particularly trypsin-like enzymes. It specifically targets the active site of proteases by covalently binding to the serine residue, thus irreversibly inhibiting their catalytic activity. Due to its specificity for serine proteases, TPCK is commonly employed to investigate the functions of these enzymes in various biological processes, including blood clotting, inflammation, and immune response.
Apart from its applications in proteomics, TPCK also acts as a useful tool in the purification and characterization of proteases. It aids in the isolation of targeted proteases from complex mixtures and enables their study in a controlled environment. TPCK’s ability to irreversibly inhibit proteases makes it a valuable reagent in enzymology and biochemical research.
It is important to note that TPCK is a potent compound and should be handled with caution. Its usage requires appropriate safety measures to ensure personal protection and minimize potential health risks.
In summary, Tosylphenylalanyl Chloromethyl Ketone (TPCK) is a chemical compound commonly used as an irreversible inhibitor of serine proteases. It is extensively utilized in biological research and proteomics to investigate and manipulate the functions of these enzymes.
Common Misspellings for TOSYLPHENYLALANYL CHLOROMETHYL KETONE
- rosylphenylalanyl chloromethyl ketone
- fosylphenylalanyl chloromethyl ketone
- gosylphenylalanyl chloromethyl ketone
- yosylphenylalanyl chloromethyl ketone
- 6osylphenylalanyl chloromethyl ketone
- 5osylphenylalanyl chloromethyl ketone
- tisylphenylalanyl chloromethyl ketone
- tksylphenylalanyl chloromethyl ketone
- tlsylphenylalanyl chloromethyl ketone
- tpsylphenylalanyl chloromethyl ketone
- t0sylphenylalanyl chloromethyl ketone
- t9sylphenylalanyl chloromethyl ketone
- toaylphenylalanyl chloromethyl ketone
- tozylphenylalanyl chloromethyl ketone
- toxylphenylalanyl chloromethyl ketone
- todylphenylalanyl chloromethyl ketone
- toeylphenylalanyl chloromethyl ketone
- towylphenylalanyl chloromethyl ketone
- tostlphenylalanyl chloromethyl ketone
- tosglphenylalanyl chloromethyl ketone
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