How Do You Spell THERMOSTABLE OPSONIN TEST?

Pronunciation: [θˈɜːmə͡ʊstˌe͡ɪbə͡l ˈɒpsənˌɪn tˈɛst] (IPA)

The spelling of "thermostable opsonin test" may seem intimidating at first, but it can actually be broken down with the help of phonetic transcription. The word "thermostable" is pronounced /θərˈməʊsteɪbl/, indicating the "th" sound at the beginning, followed by the long "o" sound and ending with a stress on the second syllable. "Opsonin" is pronounced /ɒpˈsəʊnɪn/, with a stress on the first syllable and a long "o" sound. Finally, "test" is pronounced /tɛst/, with a short "e" sound and no stress.

Meaning and Definition
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THERMOSTABLE OPSONIN TEST Meaning and Definition

  1. The thermostable opsonin test is a diagnostic test used to assess the activity of opsonins, a type of protein in the blood that enhances the phagocytosis process of white blood cells in response to pathogens or foreign particles. Opsonins essentially work as biological markers, tagging foreign bodies for destruction by the immune system.

    The test involves heating a serum sample containing opsonins at a certain temperature for a specific period. After heating, the serum is mixed with bacteria or other foreign particles. The mixture is then incubated with leukocytes (white blood cells) and observed for any signs of phagocytosis. The opsonins present in the serum play a crucial role in facilitating the engulfment and subsequent destruction of the foreign particles by the leukocytes.

    The thermostable opsonin test is particularly useful in assessing the stability and functionality of opsonins, as their activity may be compromised under certain pathological conditions or due to heat sensitivity. By subjecting the serum to thermal stress and evaluating the subsequent phagocytosis activity, this test allows for the determination of adequate opsonin levels and their proficiency.

    Overall, the thermostable opsonin test provides valuable information about the immune response by evaluating the efficiency of opsonins in their role as enhancers of phagocytosis. This test contributes to the diagnosis and monitoring of various infections, autoimmune disorders, and immunodeficiency diseases.

  2. The serum to be tested is heated to 58° or 60° C. for ten minutes or more, and then its opsonic power is measured by the phagocytic index; as the normal or thermolabile opsonin is destroyed by heating, any opsonic power remaining in the serum is assumed to be due to specific opsonin produced as a result of autoinoculation or of a previous inoculation with a vaccine.

    A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for THERMOSTABLE OPSONIN TEST

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Correct spelling for thermostable opsonin test
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