RADIOIMMUNOSORBENT TEST Meaning and
Definition
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The Radioimmunosorbent Test (RIST) is a laboratory technique used to measure the levels of specific antibodies in the blood. It is a sensitive and precise method that combines principles of radioimmunoassay and immunosorbent assay to detect and quantify the presence of specific immunoglobulins.
In the RIST procedure, a known antigen is attached to a solid surface, such as a test tube or a plastic well. The patient's blood serum is then mixed with the antigen, allowing any specific antibodies present in the serum to bind with the antigen. After a period of incubation to promote binding, any unbound antibodies are washed away.
Next, a radioactive label, usually iodine-125, is introduced. This label attaches to any remaining bound antibodies, providing a means for their detection. The level of radioactivity is measured using a specialized instrument called a scintillation counter, which can accurately quantify the amount of labeled antibodies present.
The result of the RIST is typically reported as a numerical value, reflecting the concentration of the specific antibodies being tested. This information can be helpful in the diagnosis and management of certain diseases, especially autoimmune disorders, allergic reactions, and hypersensitivity reactions. It can also assist in monitoring the effectiveness of immunotherapy or immunosuppressive treatment. Due to the high sensitivity and specificity of the RIST, it is considered a valuable tool in clinical laboratories for identifying and monitoring immune-related conditions.
Common Misspellings for RADIOIMMUNOSORBENT TEST
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Etymology of RADIOIMMUNOSORBENT TEST
The word "Radioimmunosorbent Test" (RIST) is a compound term made up of several parts:1. Radio: The term "Radio-" refers to radiation and is derived from the Latin word "radius", which means "ray". In this context, it signifies the use of radioactive substances.2. Immuno: The term "Immuno-" comes from the Latin word "immunis", meaning "exempt" or "protected". It is commonly used in medical terminology to indicate the involvement of the immune system.3. Sorbent: The term "Sorbent" is derived from the Latin word "absorbens", which means "absorbing". In this context, it refers to a material used to absorb and measure the presence of specific substances.4. Test: The term "Test" is a general word used to describe a procedure or examination done to diagnose or determine the presence of something.
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