NUCLEOFUGAL Meaning and
Definition
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Nucleofugal is an adjective used in organic chemistry to describe a molecule, functional group, or atom that has a tendency to move away or dissociate from the center of a system, particularly in response to a reaction. The term is derived from the Latin prefix "nucleo-" meaning center or nucleus, and "fugal" meaning to flee or move away. Nucleofugal species typically possess a high electron density and are capable of donating or accepting electrons.
In a chemical reaction, nucleofugal entities exhibit a propensity to dissociate or detach from a reaction center, often due to the formation of a more stable or energetically favorable product. This phenomenon is commonly observed during substitution reactions or nucleophilic substitution mechanisms, where a nucleophile replaces a leaving group. The nucleofugal species, which is usually the leaving group, tends to detach itself from the reaction center to maximize stability within the system.
The concept of nucleofugality is closely related to nucleophilicity, which refers to a species' ability to donate or share electrons during a reaction. While nucleophilicity is concerned with the addition of atoms or groups to a reaction center, nucleofugality focuses on the departure or detachment of atoms or groups from the reaction center.
Overall, the term nucleofugal describes the characteristic of a molecule, functional group, or atom to move away or dissociate from a reaction center, ultimately influencing the outcome of a chemical reaction.
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1. Moving within the cell-body in a direction away from the nucleus. 2. Moving in a direction away from a nerve nucleus, said of nerve transmission.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for NUCLEOFUGAL
- bucleofugal
- mucleofugal
- jucleofugal
- hucleofugal
- nycleofugal
- nhcleofugal
- njcleofugal
- nicleofugal
- n8cleofugal
- n7cleofugal
- nuxleofugal
- nuvleofugal
- nufleofugal
- nudleofugal
- nuckeofugal
- nucpeofugal
- nucoeofugal
- nuclwofugal
- nuclsofugal
- nucldofugal
Etymology of NUCLEOFUGAL
The word "nucleofugal" is derived from two components: "nucleo-" and "-fugal".
1. "Nucleo-" derives from the Latin word "nucleus", meaning "core" or "nucleus". In the context of chemistry, "nucleo-" refers to the center or core of an atom or molecule, which often involves a reaction or process.
2. "-Fugal" is a combining form derived from the Latin word "fugere", meaning "to flee" or "to run away". It forms various words related to fleeing, avoiding, or moving away.
Therefore, in the case of "nucleofugal", the term combines "nucleo-" (referring to the core or center) with "-fugal" (indicating movement away or avoidance).
