How Do You Spell NEURAL CREST?

1. The neural crest is a transient population of cells that arise during vertebrate embryonic development from the border between the neural plate and epidermis. It is renowned for its remarkable migratory capacity, giving rise to a diverse array of cell types and contributing to the development of various tissues and organs throughout the body.

   During embryogenesis, the neural crest cells undergo an epithelial-to-mesenchymal transition, acquiring a migratory and multipotent phenotype. They then embark on extensive migration pathways to colonize different regions of the embryo. This remarkable cell population plays a pivotal role in orchestrating the development of a wide range of structures, including the peripheral nervous system, facial bones, craniofacial muscles, pigment cells, and certain endocrine cells.

   The neural crest cells exhibit remarkable plasticity, with the ability to differentiate into various cell types depending on local signals they encounter during their migration and development. This versatility contributes to their vital role in shaping the complex architecture of the vertebrate body plan.

   Abnormalities in neural crest development can lead to a multitude of congenital malformations and diseases, such as craniofacial and cardiac defects. Therefore, understanding the intricate cellular and molecular mechanisms that govern neural crest formation, migration, and differentiation is crucial for unraveling the roots of these conditions and ultimately developing potential therapeutic interventions.

2. The line along the neural canal where the neural folds meet.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for NEURAL CREST

The word "neural crest" is derived from two components: "neural" and "crest".

The term "neural" originates from the Greek word "neuron" meaning "nerve". In this context, "neural" refers to the nervous system, specifically the group of cells that form the nerves and associated structures.

"Crest" has its roots in the Latin word "crista" meaning "ridge" or "crest". It generally refers to a raised or elevated structure.

Therefore, "neural crest" refers to a group of cells that lies along the dorsal (back) aspect of the developing nervous system during embryonic development. These cells eventually migrate and contribute to the formation of various structures including neurons, glial cells, cartilage, bone, and connective tissue in different parts of the body.

Plural form of NEURAL CREST is NEURAL CRESTS