MYOFIBROBLASTOMA Meaning and
Definition
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Myofibroblastoma is a rare benign mesenchymal tumor predominantly occurring in adult males. It is characterized by the neoplastic proliferation of myofibroblasts or spindle-shaped cells with fibroblastic features.
The term myofibroblastoma is composed of two components: "myo," meaning muscle, and "fibroblastoma," referring to a tumor originating from fibroblasts. These tumors are primarily found in breast tissues and are considered to be a type of mesenchymal stromal tumor. While myofibroblastoma most commonly affects males, it can also occur in females, particularly in postmenopausal women.
Clinically, myofibroblastomas typically present as well-circumscribed, slow-growing masses. They are usually discovered incidentally during mammographic or histopathological examinations. These tumors have various microscopic features but are predominantly composed of myofibroblasts, characterized by a central spindle-shaped nucleus and cytoplasm that expresses smooth muscle actin.
The majority of myofibroblastomas are benign, with no potential for malignancy or metastasis. However, in rare cases, they can exhibit malignant transformation or coexist with other neoplasms, necessitating careful histological examination.
Treatment options for myofibroblastoma are varied and depend on factors such as tumor size and patient preferences. Surgical excision is the primary treatment method, although conservative management can be considered for small, asymptomatic tumors.
In conclusion, myofibroblastoma is a benign tumor originating from myofibroblasts in breast tissues, predominantly affecting adult males. It is characterized by slow growth and typically presents as a well-circumscribed mass. Surgical excision is
Common Misspellings for MYOFIBROBLASTOMA
- nyofibroblastoma
- kyofibroblastoma
- jyofibroblastoma
- mtofibroblastoma
- mgofibroblastoma
- mhofibroblastoma
- muofibroblastoma
- m7ofibroblastoma
- m6ofibroblastoma
- myifibroblastoma
- mykfibroblastoma
- mylfibroblastoma
- mypfibroblastoma
- my0fibroblastoma
- my9fibroblastoma
- myodibroblastoma
- myocibroblastoma
- myovibroblastoma
- myogibroblastoma
- myotibroblastoma
Etymology of MYOFIBROBLASTOMA
The word "myofibroblastoma" is derived from the Greek roots "myo-" meaning muscle, "fibr(o)-" meaning fibrous tissue, "blast(o)-" meaning immature or precursor cell, and "-oma" meaning tumor or mass.
"Myo-" refers to the muscle-like characteristics of the cells involved in this type of tumor, while "fibroblast" refers to the type of connective tissue cells that are present. The suffix "-oma" indicates that it is a benign tumor or mass composed of myofibroblasts.
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