META IODOBENZYLGUANIDINE Meaning and
Definition
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Meta-iodobenzylguanidine (MIBG) is a chemical compound that is primarily used in nuclear medicine for diagnostic and therapeutic purposes. It is an iodine-labeled radiopharmaceutical derived from guanidine and benzylguanidine compounds. MIBG has a structure similar to the neurotransmitter norepinephrine, which allows it to selectively target and bind to specialized cells called neuroendocrine cells.
As a diagnostic agent, MIBG is used to detect and visualize certain types of tumors, particularly neuroblastomas and pheochromocytomas. These tumors often originate from neuroendocrine tissue and possess receptors that strongly bind to MIBG. By combining MIBG with a radioactive isotope, typically iodine-123 or iodine-131, doctors can track the movement and distribution of MIBG within the patient's body using specialized imaging techniques such as single-photon emission computed tomography (SPECT). This helps in identifying the location, size, and activity of the tumor.
In therapeutic applications, MIBG labeled with a more potent radioactive isotope like iodine-131 is utilized for targeted radionuclide therapy. The emitted radiation selectively damages cancer cells, working as a form of internal radiation therapy. MIBG therapy is particularly effective for the treatment of neuroendocrine tumors that have high uptake and expression of MIBG receptors.
Although MIBG has been primarily used in nuclear medicine, there is ongoing research to explore its potential applications in targeted drug delivery and treatment of other conditions, including certain types of heart diseases and congestive heart failure.
Common Misspellings for META IODOBENZYLGUANIDINE
- neta iodobenzylguanidine
- keta iodobenzylguanidine
- jeta iodobenzylguanidine
- mwta iodobenzylguanidine
- msta iodobenzylguanidine
- mdta iodobenzylguanidine
- mrta iodobenzylguanidine
- m4ta iodobenzylguanidine
- m3ta iodobenzylguanidine
- mera iodobenzylguanidine
- mefa iodobenzylguanidine
- mega iodobenzylguanidine
- meya iodobenzylguanidine
- me6a iodobenzylguanidine
- me5a iodobenzylguanidine
- metz iodobenzylguanidine
- mets iodobenzylguanidine
- metw iodobenzylguanidine
- metq iodobenzylguanidine
- meta uodobenzylguanidine
Etymology of META IODOBENZYLGUANIDINE
The word "meta Iodobenzylguanidine" is a chemical compound and its etymology can be broken down as follows:
- "Meta" refers to the meta position on the benzene ring, indicating that the iodine atom is attached to the carbon atom next to the two carbon atoms directly attached to the benzene ring.
- "Iodo" refers to iodine, which is an element.
- "Benzyl" refers to the benzyl group, which is a substituent derived from toluene, consisting of a phenyl group (benzene ring) with a methyl group attached.
- "Guanidine" refers to guanidine, which is a compound containing a central carbon atom bonded to three nitrogen atoms.
