HIV INTEGRASE Meaning and
Definition
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HIV integrase is an enzyme that plays a crucial role in the replication of the human immunodeficiency virus (HIV) within the host's cells. It is a viral protein responsible for the integration of the viral genome into the DNA of the infected cell. This process is essential for the establishment of a permanent infection and the production of new viral particles.
HIV integrase works by cleaving the host cell's DNA and inserting the viral DNA into the host cell's genome. The enzyme recognizes specific DNA sequences at both ends of the viral DNA, known as long terminal repeats (LTRs), and catalyzes the integration process. This integration allows the viral genes to be transcribed and translated by the host cell's machinery, leading to the production of new viral proteins and eventually the release of mature viral particles.
The inhibition of HIV integrase has been an important target for the development of antiretroviral drugs aimed at treating HIV infection. Integrase inhibitors are a class of medications that specifically bind to the integrase enzyme, preventing its activity and thereby inhibiting viral replication. These drugs have been effective in suppressing viral load and maintaining the health of individuals living with HIV.
Understanding the function and mechanisms of HIV integrase has provided valuable insights for the development of therapeutic interventions against HIV, contributing to the management of this global health concern.
Common Misspellings for HIV INTEGRASE
- giv integrase
- biv integrase
- niv integrase
- jiv integrase
- uiv integrase
- yiv integrase
- huv integrase
- hjv integrase
- hkv integrase
- hov integrase
- h9v integrase
- h8v integrase
- hic integrase
- hib integrase
- hig integrase
- hif integrase
- hiv untegrase
- hiv jntegrase
- hiv kntegrase
- hiv ontegrase
Etymology of HIV INTEGRASE
The word "HIV Integrase" is a combination of two terms: "HIV" and "Integrase".
1. HIV: The acronym "HIV" stands for Human Immunodeficiency Virus. It is a retrovirus that causes acquired immunodeficiency syndrome (AIDS), a condition that weakens the immune system. The term HIV was coined in 1986 by an international scientific conference on AIDS.
2. Integrase: Integrase is a term derived from the combining form "inte-" meaning "between, into" and "gras-" from the Latin verb "gradi" meaning "to step". Integrase is an enzyme that plays a crucial role in the replication of retroviruses, including HIV. It catalyzes the integration of the viral DNA into the host cell's DNA during the viral replication process.
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