FEEDER LAYER Meaning and
Definition
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A feeder layer, in the context of cell culture, refers to a layer of specialized cells that are used to support the growth of another type of cells. It is positioned as a base layer in a culture dish or flask to provide a suitable environment for the growth and proliferation of the target cells.
The feeder layer typically consists of a specific type of cells, often fibroblasts, that secrete various necessary factors and nutrients, promoting the survival and growth of the cultured cells. These factors may include growth factors, vitamins, hormones, and extracellular matrix proteins, among others. The feeder layer is usually derived from a different species or tissue type than the target cells, which prevents the feeder cells from overgrowing and contaminating the cultured cells.
The purpose of using a feeder layer is to maintain the target cells in an undifferentiated state or to support their specific growth requirements. It allows the cultured cells to adhere and spread on a suitable substrate while protecting them from adverse conditions. Feeder layers are commonly utilized in stem cell research, as they provide a supportive microenvironment for the maintenance and expansion of embryonic or induced pluripotent stem cells.
In summary, a feeder layer is a layer of specialized cells that provide essential factors and support for the growth and maintenance of cultured cells, ensuring their survival, proliferation, and desired physiological properties.
Common Misspellings for FEEDER LAYER
- deeder layer
- ceeder layer
- veeder layer
- geeder layer
- teeder layer
- reeder layer
- fweder layer
- fseder layer
- fdeder layer
- freder layer
- f4eder layer
- f3eder layer
- fewder layer
- fesder layer
- fedder layer
- ferder layer
- fe4der layer
- fe3der layer
- feeser layer
- feexer layer
Etymology of FEEDER LAYER
The word "feeder layer" originates from the combination of the words "feeder" and "layer".
- "Feeder" refers to something that provides nourishment or support to something else. In the context of cell culture, a feeder layer is a layer of cells that provides essential nutrients and growth factors to help support the growth of other cells.
- "Layer" refers to a sheet, level, or coating of something. In the case of a feeder layer, it refers to the layer of cells that are added on top of another culture to nourish and support the growth of the desired cells.
Therefore, the term "feeder layer" is used in cell culture to describe a layer of cells that acts as a source of support and nutrients for the growth of other cells.
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