FC EPSILON RI Meaning and
Definition
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Fc epsilon RI stands for the high-affinity receptor for immunoglobulin E (IgE). It is a transmembrane receptor found on the surface of mast cells and basophils, which are types of white blood cells involved in immune responses and allergic reactions.
The Fc epsilon RI receptor consists of four subunits, including one alpha chain, one beta chain, and two gamma chains. The alpha chain binds to the Fc portion of IgE antibodies that have been bound to an allergen. This interaction triggers a signaling cascade within the cell, leading to the release of various mediators, such as histamine, cytokines, and leukotrienes. These mediators play a crucial role in initiating and amplifying the immune response and inflammatory processes associated with allergies.
Fc epsilon RI has a high affinity for IgE, meaning it can bind IgE antibodies even at low concentrations. This property allows mast cells and basophils to respond rapidly and specifically to allergens, leading to the release of allergic mediators and the development of allergic symptoms. It also contributes to the sustained activation of these cells in chronic allergic conditions.
Understanding the function and regulation of Fc epsilon RI is crucial for developing therapeutic strategies to treat allergies and related immune disorders. Targeting this receptor may help to inhibit or modulate the allergic response, providing relief to individuals suffering from allergic diseases.
Common Misspellings for FC EPSILON RI
- dc epsilon ri
- cc epsilon ri
- vc epsilon ri
- gc epsilon ri
- tc epsilon ri
- rc epsilon ri
- fx epsilon ri
- fv epsilon ri
- ff epsilon ri
- fd epsilon ri
- fc wpsilon ri
- fc spsilon ri
- fc dpsilon ri
- fc rpsilon ri
- fc 4psilon ri
- fc 3psilon ri
- fc eosilon ri
- fc elsilon ri
- fc e-silon ri
- fc e0silon ri
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