ENDODEOXYRIBONUCLEASE HPAII Meaning and
Definition
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Endodeoxyribonuclease HpaII is a specific type of restriction enzyme that is derived from the bacteria Haemophilus parainfluenzae strain HpaII. It belongs to the endonuclease category and displays high specificity for certain DNA sequences.
This enzyme recognizes and cleaves DNA molecules at specific target sites, known as recognition sequences or restriction sites. In the case of HpaII, this recognition site is 5’-CCGG-3’, which means that it can only cut DNA strands when they contain the sequence CC and GG in immediate succession.
Once the enzyme locates its specific recognition site, it cleaves the phosphodiester bonds between the third and fourth nucleotide in both DNA strands. This creates a double-stranded DNA break, resulting in two shorter DNA fragments.
Endodeoxyribonuclease HpaII, like other restriction enzymes, plays an essential role in nature by protecting bacteria from invasive viruses and foreign DNA. It is commonly utilized in molecular biology research and genetic engineering techniques as a tool to manipulate DNA. Researchers can use this enzyme to cut DNA at specific sites, enabling them to isolate and study specific gene sequences or create precise DNA fragments that can be useful for various experimental purposes. The ability of HpaII to cut DNA selectively at defined recognition sequences adds significant value to its applications in molecular biology and genetics research.
Common Misspellings for ENDODEOXYRIBONUCLEASE HPAII
- wndodeoxyribonuclease hpaii
- sndodeoxyribonuclease hpaii
- dndodeoxyribonuclease hpaii
- rndodeoxyribonuclease hpaii
- 4ndodeoxyribonuclease hpaii
- 3ndodeoxyribonuclease hpaii
- ebdodeoxyribonuclease hpaii
- emdodeoxyribonuclease hpaii
- ejdodeoxyribonuclease hpaii
- ehdodeoxyribonuclease hpaii
- ensodeoxyribonuclease hpaii
- enxodeoxyribonuclease hpaii
- encodeoxyribonuclease hpaii
- enfodeoxyribonuclease hpaii
- enrodeoxyribonuclease hpaii
- eneodeoxyribonuclease hpaii
- endideoxyribonuclease hpaii
- endkdeoxyribonuclease hpaii
- endldeoxyribonuclease hpaii
- endpdeoxyribonuclease hpaii
Etymology of ENDODEOXYRIBONUCLEASE HPAII
The word "Endodeoxyribonuclease HpaII" has the following etymology:
1. "Endo-" is a prefix of Greek origin meaning "within" or "inside".
2. "Deoxyribonuclease" is a compound word. "Deoxyribo-" is a prefix referring to deoxyribose, a sugar found in DNA molecules. "Nuclease" is a combination of "nucl-" derived from the Latin word "nucleus", meaning kernel or inner part, and "-ase", a suffix indicating an enzyme.
3. "HpaII" refers to the enzyme named after the bacterium from which it was initially isolated, Haemophilus parainfluenzae, strain II.
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