CREST SYNDROME Meaning and
Definition
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Crest syndrome, also known as limited cutaneous systemic sclerosis or limited systemic scleroderma, is a type of autoimmune disorder characterized by the presence of certain clinical manifestations and the positive presence of antibodies known as anticentromere antibodies. This condition primarily affects the skin, blood vessels, and internal organs.
The term "crest" is an acronym for the five main clinical features seen in this syndrome: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. Calcinosis refers to the formation of calcium deposits in the skin and soft tissues, often leading to the development of painful lesions. Raynaud's phenomenon is a condition where the fingers, toes, and other extremities become cold and numb due to reduced blood flow. Esophageal dysmotility refers to impaired functioning of the esophagus, resulting in difficulty swallowing and heartburn. Sclerodactyly involves the hardening and tightening of the skin on the fingers and toes. Telangiectasia is the visible enlargement of blood vessels near the surface of the skin, causing red spots or lines.
In addition to these symptoms, individuals with crest syndrome may also experience respiratory problems, joint pain, muscle weakness, fatigue, and gastrointestinal issues. The disease can progress slowly over time and potentially affect vital organs such as the heart, lungs, or kidneys.
Treatment for crest syndrome primarily focuses on managing and alleviating the symptoms experienced by the individual. This may involve medication for controlling blood pressure, reducing inflammation, and relieving other specific symptoms. Additionally, physical therapy, occupational therapy, and lifestyle modifications are often recommended to improve the patient's quality of life. Close monitoring of affected organs and regular follow-up with healthcare professionals is crucial for
Common Misspellings for CREST SYNDROME
- xrest syndrome
- vrest syndrome
- frest syndrome
- drest syndrome
- ceest syndrome
- cdest syndrome
- cfest syndrome
- ctest syndrome
- c5est syndrome
- c4est syndrome
- crwst syndrome
- crsst syndrome
- crdst syndrome
- crrst syndrome
- cr4st syndrome
- cr3st syndrome
- creat syndrome
- crezt syndrome
- crext syndrome
- credt syndrome
Etymology of CREST SYNDROME
The term "CREST syndrome" is an acronym derived from the five main symptoms of the condition: Calcinosis, Raynaud's phenomenon, Esophageal dysmotility, Sclerodactyly, and Telangiectasia. Each letter represents a distinctive symptom commonly observed in patients with CREST syndrome. This acronym was first used by Dr. Paul Klemperer and Dr. Thomas Synder in the 1960s to describe a subset of systemic sclerosis, also known as scleroderma.
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