CONGLUTINATING COMPLEMENT ABSORPTION TEST Meaning and
Definition
-
The Conglutinating Complement Absorption Test (CCAT) is a laboratory technique used to measure the amount of complements absorbed by an antigen-antibody reaction. Complements are proteins in the blood plasma that play a crucial role in the immune system's ability to destroy pathogens and foreign substances. This test specifically assesses the level of complement absorption observed during the conglutination process.
The conglutination process refers to the clumping of antigens and antibodies when they come into contact with each other. During this process, complements present in the blood are utilized to facilitate the clumping together of the antigen-antibody complexes to neutralize the threat. The complements are subsequently absorbed or consumed in the complex formation, reducing their concentration in the serum.
In the CCAT, a known amount of specific antibody is mixed with a measured quantity of diluted patient or animal serum containing the antigen. The mixture is incubated under controlled conditions, allowing the antigens and antibodies to react and form complexes. After incubation, the mixture is centrifuged to isolate the complexes from the remaining serum.
The supernatant obtained after centrifugation is then tested to determine the amount of complements absorbed during the process. The CCAT quantifies the remaining free complements in the supernatant by measuring their activity level. The result of the test is expressed as the percentage of complement absorption, indicating the efficiency of the complex formation.
The Conglutinating Complement Absorption Test is primarily utilized in immunological studies and diagnosis of various diseases such as autoimmune disorders, hypersensitivity reactions, and immune deficiencies. It provides valuable insights into the immunological interactions occurring in the body and aids in identifying and monitoring immune system dysfunctions.
Common Misspellings for CONGLUTINATING COMPLEMENT ABSORPTION TEST
- xonglutinating complement absorption test
- vonglutinating complement absorption test
- fonglutinating complement absorption test
- donglutinating complement absorption test
- cinglutinating complement absorption test
- cknglutinating complement absorption test
- clnglutinating complement absorption test
- cpnglutinating complement absorption test
- c0nglutinating complement absorption test
- c9nglutinating complement absorption test
- cobglutinating complement absorption test
- comglutinating complement absorption test
- cojglutinating complement absorption test
- cohglutinating complement absorption test
- conflutinating complement absorption test
- convlutinating complement absorption test
- conblutinating complement absorption test
- conhlutinating complement absorption test
- conylutinating complement absorption test
- contlutinating complement absorption test
Infographic
Add the infographic to your website:
