How Do You Spell BASEMENT MEMBRANE?

1. A basement membrane is a specialized extracellular matrix structure that is found in the tissues of various organisms. It is a thin, sheet-like layer of connective tissue that sits beneath the epithelial cells and surrounds other cell types, providing structural support and anchorage. The basement membrane is made up of several components, including collagen fibers, laminins, proteoglycans, and other structural proteins.

   Functionally, the basement membrane acts as a physical barrier, separating different tissue layers and preventing the movement of cells between them. It also provides mechanical support to the overlying epithelial cells and maintains the structural integrity of the tissue. Additionally, the basement membrane acts as a filtration system, regulating the passage of molecules and nutrients between the tissues.

   The basement membrane plays a crucial role in various physiological processes, including development, tissue regeneration, and wound healing. It provides an environment for cells to anchor and form specialized structures, such as blood vessels and nerve fibers. It also helps in cell signaling and communication by interacting with receptors on the cell surface.

   Any disruption or abnormalities in the basement membrane can lead to various pathological conditions. For example, defects in the basement membrane are associated with certain genetic disorders, such as Alport syndrome and epidermolysis bullosa. Furthermore, changes in the basement membrane have been observed in various diseases, including cancer, fibrosis, and chronic kidney disease, affecting tissue function and integrity.

2. • A very thin membrane beneath the epithelium of a mucous membrane and beneath the secreting glands opening on its surface.

   • A thin structureless layer underlying the epithelium of the integument and mucous membrane, and serving as a support for numerous delicate structures.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for BASEMENT MEMBRANE

The word "basement membrane" originates from the Latin word "basementum", meaning foundation or base, and the English word "membrane", referring to a thin, sheet-like structure. The term was first coined in the 19th century to describe a specialized extracellular matrix located beneath the epithelium in many tissues of the body. It was named so due to its position at the base or bottom of the epithelial cells.

Idioms with the word BASEMENT MEMBRANE

Similar spelling word for BASEMENT MEMBRANE

Plural form of BASEMENT MEMBRANE is BASEMENT MEMBRANES

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