ASPARAGINE DEAMINASE Meaning and
Definition
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Asparagine deaminase is a type of enzyme that catalyzes the conversion of the amino acid asparagine into the amino acid aspartic acid, by removing the amino group from asparagine. This enzymatic reaction is called deamination, which involves the removal of an amino group from a compound. Asparagine deaminase is an important enzyme in various biological processes, including amino acid metabolism and cellular homeostasis.
Asparagine deaminase plays a crucial role in the nitrogen metabolism of various organisms, serving as a regulatory switch for the utilization of nitrogen sources. By catalyzing the deamination of asparagine, this enzyme is involved in the interconversion of nitrogenous compounds, contributing to the recycling of nitrogen and regulation of cellular nitrogen levels.
In addition to its metabolic role, asparagine deaminase has attracted interest for its potential therapeutic applications in various fields, especially in cancer research. Asparagine deaminase activity in certain tumors has been associated with reduced sensitivity to chemotherapeutic agents, as tumor cells rely on high levels of asparagine for growth. As a result, inhibiting asparagine deaminase activity has been explored as a potential strategy to enhance the efficacy of chemotherapy drugs.
In summary, asparagine deaminase is an enzyme that mediates the conversion of asparagine to aspartic acid through the process of deamination, playing a vital role in the regulation of nitrogen metabolism and possessing potential therapeutic implications in diseases such as cancer.
Common Misspellings for ASPARAGINE DEAMINASE
- zsparagine deaminase
- ssparagine deaminase
- wsparagine deaminase
- qsparagine deaminase
- aaparagine deaminase
- azparagine deaminase
- axparagine deaminase
- adparagine deaminase
- aeparagine deaminase
- awparagine deaminase
- asoaragine deaminase
- aslaragine deaminase
- as-aragine deaminase
- as0aragine deaminase
- aspzragine deaminase
- aspsragine deaminase
- aspwragine deaminase
- aspqragine deaminase
- aspaeagine deaminase
- aspadagine deaminase
Etymology of ASPARAGINE DEAMINASE
The word "asparagine" in "asparagine deaminase" originates from the French word "asparagine". The term "asparagine" was coined by the French chemist Pierre Jean Robiquet in 1806 when he isolated this particular compound from asparagus extracts. The name "asparagine" is derived from "asparagus", as this amino acid was initially identified in asparagus plants.
The word "deaminase" is derived from the Latin term "de" which means "to remove" or "away from", and "amin(a)" which refers to "amino group" (-NH2), and the suffix "-ase" commonly used to indicate an enzyme. Therefore, "deaminase" refers to an enzyme that catalyzes the removal or substitution of an amino group from a molecule.
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