ASEB is an acronym that stands for "Adult-onset Still's disease (AOSD) and autoinflammatory syndromes with evanescent or episodic neutrophilia and2 hypergammaglobulinemia, in short "ASEB syndrome." It is a rare autoinflammatory condition characterized by recurring fever episodes, joint pain, and other systemic manifestations.
Adult-onset Still's disease (AOSD) is a type of inflammatory disorder typically diagnosed in individuals over 16 years old. It is characterized by high fevers that occur daily or every other day, along with joint pain, rash, sore throat, and swollen lymph nodes. AOSD can also affect various organs, such as the liver, lungs, heart, and kidneys.
Autoinflammatory syndromes with evanescent or episodic neutrophilia and hypergammaglobulinemia refer to a group of disorders that involve excessive activation of the immune system. Neutrophils are a type of white blood cell that plays a crucial role in the body's defense against infections. Hypergammaglobulinemia refers to high levels of gamma globulins (antibodies) in the bloodstream. These conditions are characterized by periodic episodes of fever, joint pain, skin rash, and other inflammatory symptoms.
ASEB syndrome is an umbrella term used to describe the combination of AOSD and autoinflammatory syndromes with evanescent or episodic neutrophilia and hypergammaglobulinemia. The exact cause of ASEB syndrome is still not fully understood, and there is no specific cure. Treatment typically focuses on managing symptoms and reducing inflammation. Anti-inflammatory medications, corticosteroids, and immunosuppressive drugs may be prescribed to alleviate symptoms and
