ANAPLEROTIC REACTION Meaning and
Definition
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Anaplerotic reaction refers to a biochemical process that replenishes or restores a depleted intermediate metabolite in a metabolic pathway. These reactions play a crucial role in maintaining the balance of metabolic flux or constant pool sizes of metabolites inside a cell.
In metabolic pathways, intermediates are constantly consumed or utilized for energy production, biosynthesis, or other cellular processes. Anaplerotic reactions act as reserve mechanisms to ensure a continuous supply of the intermediates when they become limiting due to high demand or depletion caused by other reactions.
These reactions often involve the replenishment of key intermediates, such as those involved in the Krebs cycle (also known as the citric acid cycle or tricarboxylic acid cycle), which is a central metabolic pathway involved in energy generation. Anaplerosis ensures the availability of these intermediates, such as oxaloacetate or alpha-ketoglutarate, which are essential for functioning of the cycle.
Anaplerotic reactions can occur via various mechanisms, including enzymatic reactions or the utilization of specific metabolic pathways dedicated to generating the depleted intermediate. These reactions are tightly regulated to achieve homeostasis within the cell, maintaining the equilibrium between consumption and replenishment of intermediates.
Overall, anaplerotic reactions are critical in maintaining metabolic balance and ensuring appropriate levels of key intermediates for cellular processes. They serve as a compensatory mechanism to counteract the depletion of metabolites and the potential disruption of metabolic pathways, ultimately supporting the overall functionality and survival of the cell.
Common Misspellings for ANAPLEROTIC REACTION
- znaplerotic reaction
- snaplerotic reaction
- wnaplerotic reaction
- qnaplerotic reaction
- abaplerotic reaction
- amaplerotic reaction
- ajaplerotic reaction
- ahaplerotic reaction
- anzplerotic reaction
- ansplerotic reaction
- anwplerotic reaction
- anqplerotic reaction
- anaolerotic reaction
- anallerotic reaction
- ana0lerotic reaction
- anapkerotic reaction
- anapperotic reaction
- anapoerotic reaction
- anaplwrotic reaction
- anaplsrotic reaction
Etymology of ANAPLEROTIC REACTION
The word "anaplerotic" is derived from the Greek word "anaplēroun" which means "to fill up or to complete". In the context of biochemistry, an "anaplerotic reaction" refers to a metabolic reaction that helps replenish or fill up a depleted pool of certain metabolites or intermediates in a metabolic pathway. The term was first used by Fritz Lipmann, a German-American biochemist, in the mid-20th century to describe these specific reactions.
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